Master’s student Coleman Khupe from the Department of Chemical Engineering at Stellenbosch University is conducting research on the preparation and performance evaluation of cryogels for the encapsulation of micronutrients and bioactive compounds. The project focuses on producing cryogels using pectin derived from waste orange peels through the freeze-drying technique. The primary aim is to encapsulate model bioactive compounds, specifically ferulic acid, quercetin, and retinol, and to evaluate the performance of these cryogels under storage and in-vitro conditions.
Coleman’s research involves several objectives, starting with the optimisation of pectin extraction and gel formation using response surface methodology. The preparation and characterisation of the cryogels will include assessments of their morphology and mechanical properties, both before and after loading the bioactive compounds. The study will also determine the loading and release profiles of these compounds while evaluating potential interactions between the matrix and the compounds themselves. Furthermore, the performance of the cryogels will be assessed under in-vitro conditions and during storage, alongside measurement of the antioxidant properties of the compounds and their respective bioavailability.
One of the anticipated outcomes of this research is the development of a technology that allows for the sustained slow release of micronutrients and bioactive compounds. This advancement could improve the bioavailability and stability of quercetin, ferulic acid, and retinol, which are known for their health benefits but often suffer from poor solubility and instability.
The potential applications of this research include food functionalisation and fortification, which may lead to improved health benefits, particularly in addressing degenerative ailments. Additionally, the study aims to valorise waste orange peels, aligning with global sustainability goals and contributing to a zero-waste approach while enhancing the economic prospects of the fruit processing industry. Coleman’s research reflects a commitment to advancing knowledge in the fields of nutrition and sustainability.
Supervisor: Prof. Annie Chimpango – Department of Chemical Engineering, Stellenbosch University
